What Other Drugs Could Interact With This Medication
There may be an interaction between naproxen sodium and any of the following:
- acetylsalicylic acid
- aminoglycoside antibiotics
- angiotensin converting enzyme inhibitors
- angiotensin receptor blockers
- beta-adrenergic blockers
- calcium channel blockers
- oral corticosteroids
- low molecular weight heparins
- multivitamins with Vitamin A, D, E
- other NSAIDs
- quinolone antibiotics
- selective serotonin reuptake inhibitors
- serotonin/norepinephrine reuptake inhibitors
- sodium phosphates
- tricyclic antidepressants
If you are taking any of these medications, speak with your doctor or pharmacist. Depending on your specific circumstances, your doctor may want you to:
- stop taking one of the medications,
- change one of the medications to another,
- change how you are taking one or both of the medications, or
- leave everything as is.
An interaction between two medications does not always mean that you must stop taking one of them. Speak to your doctor about how any drug interactions are being managed or should be managed.
All material copyright MediResource Inc. 1996 2022. Terms and conditions of use. The contents herein are for informational purposes only. Always seek the advice of your physician or other qualified health provider with any questions you may have regarding a medical condition. Source: www.medbroadcast.com/drug/getdrug/Aleve-Liquid-Gels
Difference Between Naproxen And Tylenol
Naproxen works well for treating mild to moderate pain or inflammation.
Tylenol effectively reduces fever and relieves pain, but it doesnt lower inflammation and swelling.
Naproxen is good for relieving pain from common conditions like menstrual cramps, toothaches, and arthritis.
Works well to relieve pain and fevers. Good for menstrual cramps, toothaches, body aches, and mild arthritis pain.
Naproxen causes fewer stomach problems and is generally safe to use. Naproxen is not safe for pregnant women and people who are above the age of 60. Could cause kidney problems and stomach bleeding if taken for a longer period.
Tylenol causes less upset stomach, ulcers, bruising, and bleeding than other pain medications. It doesnt cause kidney damage and is also safe to use for people suffering from heart problems or in case of pregnancy.
Naproxen can raise the risk of getting blood clots, heart attack, or stroke.
Drinking alcohol while taking Tylenol can damage the liver
How Long Should I Use An Over
Dont use an over-the-counter NSAID continuously for more than three days for fever, and 10 days for pain, unless your doctor says its okay. Over-the-counter NSAIDs work well in relieving pain, but theyre meant for short-term use.
If your doctor clears you to take NSAIDs for a long period of time, you and your doctor should watch for harmful side effects. If you notice bad side effects your treatment may need to be changed.
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What Are Common Side Effects Of Nsaids
You may have side effects if you take large doses of NSAIDs, or if you take them for a long time. Some side effects are mild and go away, while others are more serious and need medical attention. Unless your doctor tells you to do so, don’t take an over-the-counter NSAID with a prescription NSAID, multiple over-the-counter NSAIDs or more than the recommended dose of an NSAID. Doing so could increase your risk of side effects.
The side effects listed below are the most common, but there may be others. Ask your doctor if you have questions about your specific medication.
The most frequently reported side effects of NSAIDs are gastrointestinal symptoms, such as:
- Feeling very tired and weak.
How Should You Think About Taking Nsaids In View Of The Possible Side Effects
Years ago, doctors thought of NSAIDs as being very safe. They still are acceptably safe for many people, but longer-term experience and medical studies have shown that there are definite risks. Think about these things before you start NSAIDs and consider them again if you are taking them for a while:
- Do you have risk factors for the side-effects of these medications? For example, do you have a prior history of ulcer, a known bleeding problem? Are you are higher-than-average cardiac risk, such as if you have had a heart attack, have high blood pressure or have diabetes. Older people have more GI and cardiovascular risk from NSAIDs.
- Have you been told of abnormal kidney function? NSAIDs can negatively affect kidney function.
- Will you be taking NSAIDs for a short or long time? Although heart issues have been described after short uses of NSAIDs, most of the time the problems come with prolonged use. There are situations where long-term use of NSAIDs is appropriate, but in many other situations the need for long-term NSAIDs calls for a discussion with your health care provider about possible alternatives.
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Verdict: Ibuprofen Vs Naproxen For Back Pain
So which is better for back pain: naproxen or ibuprofen? The answer is that they are equally effective and you can take either for back pain based on your preference. Not only do NSAIDs relieve pain, but they reduce any inflammation from an acute back injury. Make sure to take your NSAID with food to minimize stomach upset. You also need to take your NSAID regularly rather than as needed for the first 3-5 days after a back injury to reduce to inflammation in your back.
We do not recommend NSAIDs longer than 2 weeks without the advice of your doctor since NSAIDs can cause side effects such as stomach ulcers if taken for several months. Your doctor may recommend an antacid such as lansoprazole if you need to take an NSAID for longer. We also do not recommend NSAIDs if you have had a history of heart attack or stroke, kidney disease, or previous bleeding in your stomach or intestines.
After your back begins to feel better, you will want to try some exercises to prevent future back pain. Click on our article: 6 Best Exercises for Chronic Low Back Pain.
How To Cope With Side Effects Of Naproxen
What to do about:
- confusion if naproxen makes you feel confused, speak to your doctor.
- headache make sure you rest and drink plenty of fluids. Do not drink too much alcohol. Ask your pharmacist to recommend a painkiller. Headaches should usually go away after the first week of taking naproxen. Talk to your doctor if they last longer than a week or are severe.
- ringing in the ears if this lasts for more than 1 or 2 days, speak to your doctor as they may need to change your treatment.
- changes in vision do not drive until this side effect has worn off.
- feeling sleepy, tired or dizzy as your body gets used to naproxen, these side effects should wear off.
- dizziness if naproxen makes you feel dizzy, stop what youre doing and sit or lie down until you feel better.
- rashes it may help to take an antihistamine, which you can buy from a pharmacy. Check with the pharmacist to see what type is suitable for you.
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Symptoms That Ibuprofen Can Cause And Other Nsaids
Its important to know the names and be aware of other NSAIDs too, which can cause the same side effects as Ibuprofen:
- Cambia / Cataflam / Voltaren
- COX-2 Inhibitors
Symptoms associated with the use of NSAIDs include fluid retention, dizziness, headaches, confusion, raised liver enzymes , diarrhea, high blood pressure, hives or other skin irritation, gastric pain, nausea, ulcers of the esophagus, kidney complications and asthma. Contact your doctor immediately if you experience swollen ankles, black stools, difficulty breathing or dark, coffee colored vomit.
If youve used NSAIDs and feel concerned, consider seeing a functional medical doctor. Certain groups are at higher risk: those who are aging, those with a history of heart failure, kidney disease, diabetes, ulcers or high blood pressure. Drinking alcohol also increases risk factors. For the following symptoms consider alternative methods for healing from NSAIDs :
Symptoms Of Serious Stomach Issues
The symptoms of stomach problems after taking non-steroidal anti-inflammatory drugs , such as aspirin, ibuprofen, and naproxen, can vary from person to person. Some symptoms can be signs of something more serious like stomach bleeding or ulcers, so it important to recognise the symptoms of these serious stomach problems yourself:
- Extreme abdominal pain
- Vomiting blood or a dark substance
If you experience any of these symptoms, consult with your GP or pharmacist immediately.
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What Other Information Should I Know
Before having any laboratory test, tell your doctor and the laboratory personnel that you are taking naproxen.
If you are taking prescription naproxen, do not let anyone else take your medication. Ask your pharmacist any questions you have about refilling your prescription.
It is important for you to keep a written list of all of the prescription and nonprescription medicines you are taking, as well as any products such as vitamins, minerals, or other dietary supplements. You should bring this list with you each time you visit a doctor or if you are admitted to a hospital. It is also important information to carry with you in case of emergencies.
What Are The Side Effects Of Nsaids
The major side effects of NSAIDs are related to their effects on the stomach and bowels . Some 10% to 50% of patients are unable to tolerate treatment with NSAIDs because of side effects, including abdominal pain, diarrhea, and upset stomach. Approximately 15% of patients on long-term treatment with NSAIDs develop a peptic ulcer . Even though many of these patients with ulcers do not have symptoms and are unaware of their ulcers, they are at risk of developing serious ulcer complications, such as bleeding or perforation of the stomach.
The annual risk of serious complications is 1% to 4% with chronic treatment with NSAIDs. The risk of ulcers is higher in the elderly and individuals with rheumatoid arthritis, and those also taking steroid-containing medications , and individuals with a prior history of bleeding ulcers. Taking blood thinning medications , such as warfarin , and heparin, does not cause NSAID-related ulcers, but rather they increase bleeding if NSAID-induced ulcers occur.
A prior history of ulcers is the most important predictor of NSAID-induced ulcers. Patients with heart disease who are taking aspirin for prevention of heart attacks also are at risk, and the risk of bleeding ulcers doubles if aspirin is combined with other NSAIDs.
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What Is The Most Important Information I Should Know About Naproxen
Naproxen can increase your risk of fatal heart attack or stroke, even if you dont have any risk factors. Do not use this medicine just before or after heart bypass surgery .
Naproxen may also cause stomach or intestinal bleeding, which can be fatal. These conditions can occur without warning while you are using naproxen, especially in older adults.
You should not use naproxen if you are allergic to it, or if you have ever had an asthma attack or severe allergic reaction after taking aspirin or an NSAID.
Ask a doctor before giving naproxen to a child younger than 12 years old.
Ask a doctor or pharmacist if this medicine is safe to use if you have:
- heart disease, high blood pressure, high cholesterol, diabetes, or if you smoke
- a heart attack, stroke, or blood clot
- stomach ulcers or bleeding
Why Does It Take That Long After Aspirin To Take Naproxen
Medicines react when they are inside your body and different medicines will have different reactions so it is best to wait for at least a few hours before you could take the next medicine. However, waiting for at least half an hour could also be beneficial for the patient.
You should talk to your doctor before you want to take medicines such as aspirin and naproxen together. If you are using these medicines together then it could decrease the effectiveness in case you are using them for your heart-related issues.
Combining or adding more medicines means that you are doubling up your pain killers and this could have serious effects on your body. You should be careful before you decide o do things on your own. However, seek help from your family members or some elders if you are experiencing severe pain or some kind of other symptoms that are not supposed to happen.
Some of the most common side effects of using aspirin are stomach upset and heartburn. In case these symptoms worsen then you should immediately consult with a doctor. The doctor in the case has prescribed you this medicine then it means that the dosage that is prescribed should just be perfect for you.
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Interactions Between Naproxen And Other Medications
Naproxen may interact with certain medications or supplements. Always let your doctor and pharmacist know about any other medications or supplements that you are currently taking. The list below does not include all possible drug interactions with naproxen . Please note that only the generic name of each medication is listed below.
Using this medicine with any of the following medicines is not recommended. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.
How Nsaids Affect Your Gastrointestinal System
NSAID medications work by decreasing the production of chemicals called prostaglandins, which contribute to pain and inflammation in the body. Most NSAIDs do this by blocking COX-1 and COX-2 enzymes, which are used to make prostaglandins.
However, prostaglandins also have positive effects on the body, so blocking COX enzymes can have unwanted effects. COX-1 plays an important role in protecting the lining of the stomach. Taking NSAIDs that block COX-1 can lead to GI side effects such as abdominal pain, heartburn, nausea, and diarrhea. In extreme cases, patients may develop ulcers and life-threatening internal bleeding.
There is currently one NSAID approved in the U.S. Celebrex that blocks only COX-2. The incidence of GI side effects is lower compared to other NSAIDs, Dr. Bhana says. However, Celebrex is more expensive, and it may have more cardiovascular side effects than other NSAIDs.
So are there any NSAIDs that block COX-1 and COX-2 that are milder on the stomach than others? Studies have found that ibuprofen and meloxicam may be less likely to bother your stomach, while ketorolac, aspirin, and indomethacin are associated with a higher risk of GI problems. Read more about how to pick the right NSAID for your needs here.
That said, the specific NSAID you take isnt the most important concern, Dr. Bhana says: Excluding Celebrex, the dosage and frequency are of more concern than the particular NSAID used.
Needless to say, she no longer takes NSAIDs.
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How Does My Doctor Choose An Nsaid Thats Right For Me
In planning your treatment, your doctor looks at the effectiveness and the risks of these drugs. Your medical history, physical exam, X-rays, blood tests and presence of other medical conditions all play a part in deciding which NSAIDs will work for you.
After you start your NSAID program meet with your doctor regularly to check for any harmful side effects and, if necessary, make any changes. Blood tests or other tests may need to be done for this part of your treatment.
In What Cases Should I Check With My Doctor Before Taking Nsaids
If you have any of the following conditions or circumstances please check with your doctor before you take NSAIDs:
- Pregnancy .
- Children and teenagers with viral infections should not receive aspirin or aspirin-containing products due to the risk of Reye’s syndrome .
- Those who have an upcoming surgical procedure, including dental surgery.
- People who have three or more alcoholic beverages per day.
- Asthma that gets worse when taking aspirin.
- If you are 65 years of age or older.
- History of stroke or heart attack.
Allergic and drug interactions
- Known allergies to medications, especially aspirin, other NSAIDs and sulfa drugs.
- Nasal polyps .
- Please check with your pharmacist or healthcare provider before starting an NSAID to determine if your current medications, both prescription and OTC, and also your dietary/herbal supplements, are compatible with the NSAID. Do this especially if you are on warfarin , clopidogrel , corticosteroids , phenytoin , cyclosporine , probenecid and lithium .
- If you take diuretics to control your blood pressure, you may be at greater risk of kidney problems if you take an NSAID.
- Phenylketonuria . Some nonprescription NSAIDs are sweetened with aspartame, a source of phenylalanine.
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